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Antigenic Specificity | HDAC9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: porcine, horse, rabbit, dog |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HDAC9 Antibody detects endogenous levels of total HDAC9. Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription.Post Translational Modifications: Phosphorylated on Ser-220 and Ser-450; which promotes 14-3-3-binding, impairs interaction with MEF2, and antagonizes antimyogenic activity. Phosphorylated on Ser-240; which impairs nuclear accumulation (By similarity). Isoform 7 is phosphorylated on Tyr-1010. Phosphorylated by the PKC kinases PKN1 |
Immunogen | Immunogen: A synthesized peptide derived from human HDAC9. Tissue Specificity: Broadly expressed, with highest levels in brain, heart, muscle and testis. Isoform 3 is present in human bladder carcinoma cells (at protein level). |
Other Names | [HD 7; HD 7B; HD 9; HD7; HD7B; HD9; HDAC 7; HDAC 7B; HDAC 9; HDAC 9B; HDAC 9FL; HDAC; HDAC7; HDAC7B; HDAC9; HDAC9_HUMAN; HDAC9B; HDAC9FL; HDRP; Histone deacetylase 4/5 related protein; Histone deacetylase 7; Histone deacetylase 7B; Histone deacetylase 9; Histone deacetylase 9A; Histone deacetylase related protein; Histone deacetylase-related protein; KIAA0744; MEF2 interacting transcription repressor MITR; MEF2 interacting transcription repressor protein; MEF2-interacting transcription repressor MITR; MITR] |
Gene, Accession # | [HDAC9], Gene ID: 9734, NCBI: NP_001191073.1, UniProt: Q9UKV0 |
Catalog # | MBS9610367 |
Price | $225, $280, $340 |
Order / More Info | HDAC9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |