MRGX1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MRGX1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: MRGX1 antibody detects endogenous levels of total MRGX1. Function: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22)(PubMed:26582731). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.Similarity: Belongs to the G-protein coupled recept |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane; Multipass Membrane Protein. Tissue Specificity: Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. |
| Other Names | [GPCR; MAS related gene MRGX1; MAS related GPR member X1; MRGPRX1; MRGX1; SNSR4] |
| Gene, Accession # | [MRGX1], Gene ID: 259249, NCBI: NP_671732.3, UniProt: Q96LB2 |
| Catalog # | MBS9606443 |
| Price | $240, $280 |
| Order / More Info | MRGX1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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