Edit |   |
Antigenic Specificity | BCL7A (N-term), 1-30 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: zebrafish, mouse, Xenopus) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This BCL7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BCL7A. This gene is directly involved, with Myc and IgH, in athree-way gene translocation in a Burkitt lymphoma cell line. As aresult of the gene translocation, the N-terminal region of the geneproduct is disrupted, which is thought to be related to thepathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma.The N-terminal segment involved in the translocation includes theregion that shares a strong sequence similarity with those of BCL7Band BCL7C. Two transcript variants encoding different isoforms havebeen found for this gene. |
Immunogen | n/a |
Other Names | [B-cell CLL/lymphoma 7 protein family member A; BCL7A] |
Gene, Accession # | [BCL7A], Gene ID: 605, NCBI: NP_001019979.1, UniProt: Q4VC05 |
Catalog # | MBS9203086 |
Price | $165, $370 |
Order / More Info | BCL7A (N-term), 1-30 Antibody from MYBIOSOURCE INC. |
Product Specific References | Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009) Liang, X.S., et al. Br. J. Haematol. 146(4):418-423(2009) Morton, L.M., et al. Cancer Epidemiol. Biomarkers Prev. 18(4):1259-1270(2009) Carbone, A., et al. Genes Chromosomes Cancer 47(12):1067-1075(2008) Matsuoka, S., et al. Science 316(5828):1160-1166(2007) |