HFE Picoband Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHFE Picoband
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
ConcentrationAdd 0.2ml of distilled water will yield a concentration of 500ug/ml.
ApplicationsWestern Blot (WB)
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DescriptionDescription: Human hemochromatosis protein also known as the HFE protein is a protein which in humans is encoded by the HFE gene. The HFE gene is located on short arm of chromosome 6 at location 6p21.3. The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene.Protein Function: Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.
ImmunogenImmunogen: E Coli-derived human HFE recombinant protein (Position: Q82-R199). Human HFE shares 72.2% and 74.6% amino acid (aa) sequence identity with mouse and rat HFE, respectively. Subcellular Localization: Cell membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed in all tissues tested except brain.
Other Names[Hereditary hemochromatosis protein; HLA-H; HFE; HLAH]
Gene, Accession #[HFE], Gene ID: 3077, NCBI: NP_000401.1, UniProt: Q30201
Catalog #MBS1750424
Price$280
Order / More InfoHFE Picoband Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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