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Antigenic Specificity | NOS1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nitric Oxide Synthase (NOS) catalyses the formation of nitric oxide (NO) and citruline from L-arginine, oxygen and cofactors. Three family members have been characterized: neuronal NOS (nNOS), which is found primarily in neuronal tissue; inducible NOS (iNOS), which is induced by interferon gamma and lipopolysaccharides in the kidney and cardiovascular system; and endothelial NOS (eNOS), which is expressed in blood vessels (1). NO is a messenger molecule with diverse functions throughout the body including the maintenance of vascular integrity, homeostasis, synaptic plasticity, long-term potentiation, learning, and memory (2, 3). nNOS binds selectively to the second PDZ domain of PSD-95, and the enzymatic activity of nNOS is either downregul |
Immunogen | Immunogen: Recombinant protein of human NOS1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [NOS1; IHPS1; N-NOS; NC-NOS; NOS; Bnos; nNOS] |
Gene, Accession # | [NOS1], Gene ID: 4842, NCBI: NP_000611.1, UniProt: P29475 |
Catalog # | MBS8502849 |
Price | $310 |
Order / More Info | NOS1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Tsutsui, M. (2004) J Atheroscler Thromb 11, 41-48. 2. Son, H. et al. (1996) Cell 87, 1015-10123. 3. Hawkins, R.D. (1996) Neuron 16, 465-467. 4. Watanabe, Y. et al. (2003) Biochem J 372, 465-71. 5. Sears, C.E. et al. (2004) Philos Trans R Soc Lond B Biol Sci 359, 1021-44. |