Mouse Lyve-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse Lyve-1
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatantigen affinity purified
Size0.05 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS)
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DescriptionLYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph ve
ImmunogenImmunogen: Recombinant mouse soluble LYVE-1 (RT #S01-026). Preparation: Produced from sera of rabbits pre-immunized with highly pure (>95%) recombinant mouse soluble LYVE-1 (Ala24-Gly228) derived from insect cells.
Other Names[mouse LYVE-1; Lymphatic vessel endothelial hyaluronic acid receptor 1], [Lyve1; Lyve1; Xlkd1; Lyve-1; Crsbp-1; 1200012G08Rik; Crsbp1; Xlkd1; LYVE-1; CRSBP-1]
Gene, Accession #[Lyve-1], Gene ID: 114332, NCBI: NP_444477.2, UniProt: Q8BHCo
Catalog #MBS691161
Price$295
Order / More InfoMouse Lyve-1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Carriera et al., Cancer Res 61:8079, 2001 2. Jackson DG Trends Cardiovasc Med 13:1, 2003 3. Sleeman et al., Microsc Res Tech 55:61, 2001 4. Makinen et al., EMBO J 20 : 4762, 2001
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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