Edit |   |
---|---|
Antigenic Specificity | ECSIT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This affinity-purified antibody is directed against human ECSIT protein. The product was purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross reactivity with ECSIT protein from human and mouse sources based on 100% homology with the immunizing sequence. Reactivity against homologues from other sources is not known. Activation of NF-kB as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses (reviewed in 1). Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 (2) to kinases such as IRAK (3) and other intermediates such as TNF receptor associated factor (TRAF)-6 (4). ECSIT |
Immunogen | Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the carboxy terminus of human ECSIT protein. |
Other Names | [ECSIT; evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; ECSIT signalling integrator] |
Gene, Accession # | [ECSIT], Gene ID: 51295 |
Catalog # | MBS4156742 |
Price | $540 |
Order / More Info | ECSIT Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |