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Antigenic Specificity | AATF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Binding to the pocket region of RB1 by AATF may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. |
Immunogen | Immunogen: AATF antibody (HRP) was raised in Rabbit using recombinant human Protein AATF protein as the immunogen Conjugate: HRP |
Other Names | [Rabbit AATF (HRP); AATF; AATF; HSPC277; CHE1; DED; Apoptosis antagonizing transcription factor; Rb binding protein Che 1] |
Gene, Accession # | [AATF], NCBI: JAO53224.1 |
Catalog # | MBS5310383 |
Price | $355 |
Order / More Info | AATF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |