XIAP Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | XIAP |
| Clone | [1020CT7.2.2] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, k |
| Format | unconjugated |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This XIAP antibody is generated from a mouse immunized with a recombinant protein human XIAP. Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive state. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and the target proteins for its E3 ubiquitin-protein ligase activity include: RIPK1, CASP3, CASP7, CASP8, CASP9, MAP3K2/MEKK2, DIABLO/SMAC, AIFM1, CCS and B |
| Immunogen | n/a |
| Other Names | [Purified Mouse (Mab); E3 ubiquitin-protein ligase XIAP; 632-; Baculoviral IAP repeat-containing protein 4; IAP-like protein; ILP; hILP; Inhibitor of apoptosis protein 3; IAP-3; hIAP-3; hIAP3; X-linked inhibitor of apoptosis protein; X-linked IAP; XIAP; API3; BIRC4; IAP3] |
| Gene, Accession # | [XIAP], Gene ID: 331, NCBI: NP_001158.2, UniProt: P98170 |
| Catalog # | MBS9215398 |
| Price | $165, $370 |
| Order / More Info | XIAP Antibody from MYBIOSOURCE INC. |
| Product Specific References | Duckett C.S.,et al.EMBO J. 15:2685-2694(1996).Liston P.,et al.Nature 379:349-353(1996).Ross M.T.,et al.Nature 434:325-337(2005).Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.Deveraux Q.L.,et al.Nature 388:300-304(1997). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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