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Antigenic Specificity | DC-UbP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DC-UbP [Rabbit antibody to peptide corresponding to aa 197-212 of human DC-UbP.]. This antibody recognizes human, mouse, and rat DC-UbP. DC-UbP is a 26 kDa ubiquitin-like protein from dendritic cells comprised of 106 amino acids. The ubiquitin domain in DC-UbP shares 28.6% identity with ubiquitin, but it does not have the conserved C-terminus Gly-Gly of ubiquitin required for ubiquitinization. DC-UbP is found in cytoplasm (particularly in mitochondria), and DC-UbP mRNA is expressed in various tumor cell types, but not in normal adult human tissues, which suggests a role for DC-UbP in tumorigenesis. In addition, DC-UbP appears to be downregulated during cellular differentiation and apoptosis. |
Immunogen | Immunogen: Synthetic peptide corresponding to amino acids197-212 (SGRPLTDKMKFEELKI) of human DC-UbP precursor conjugated to KLH at the N-terminus. This sequence is 93% identical with those of mouse and rat DC-UbP. |
Other Names | [DC-UbP], [UBTD2; UBTD2; DCUBP; MGC30022; DCUBP] |
Gene, Accession # | Gene ID: 92181, NCBI: NP_689490.2, UniProt: Q8WUN7 |
Catalog # | MBS194393 |
Price | $335 |
Order / More Info | DC-UbP Antibody from MYBIOSOURCE INC. |
Product Specific References | Liu S, et al. 2003 Biochem Biophys Res Commun 300: 800-805. |