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Antigenic Specificity | BACE1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.7 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total BACE1 protein. Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to residues near the C terminal of human beta-site APP-cleaving enzyme 1 |
Other Names | [ASP2; BACE; HSPC104] |
Gene, Accession # | [BACE1], Gene ID: 23621, NCBI: NP_001193978.1, UniProt: P56817 |
Catalog # | MBS9407605 |
Price | $255 |
Order / More Info | BACE1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |