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Antigenic Specificity | CXCR4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CXCR4 Antibody detects endogenous levels of total CXCR4. Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development. |
Immunogen | Immunogen: A synthesized peptide derived from human CXCR4 |
Other Names | [CD184; CXCR4; C-X-C chemokine receptor type 4; FB22; Fusin; HM89; LCR1; LESTR; NPYRL; SDF-1 receptor; Stromal cell- derived factor 1 receptor] |
Gene, Accession # | [CXCR4], Gene ID: 7852, NCBI: NP_001008540.1, UniProt: P61073 |
Catalog # | MBS4750152 |
Price | $335 |
Order / More Info | CXCR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |