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Antigenic Specificity | STAT6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo-or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. |
Immunogen | Immunogen: STAT6 antibody was raised in Rabbit using the peptide sequence around phosphorylation site of Tyrosine 641 (R-G-Y(p)-V-P) derived from Human STAT6 as the immunogen. |
Other Names | [Rabbit STAT6; STAT6; STAT6; Phospho Tyr641; STAT-6; STAT-6; D12S1644; STAT6; STAT 6; IL-4-STAT; STAT6B; STAT6C; STAT 6; Signal transducer and activator of transcription 6] |
Gene, Accession # | [STAT6], Gene ID: 6778, NCBI: NP_001171552.1 |
Catalog # | MBS5309494 |
Price | $295 |
Order / More Info | STAT6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |