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Antigenic Specificity | Nop30 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation. Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and the caspase family of proteases. CARD domain containing cell death regulators include RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD. An alternate splicing isoform of ARC was identified as Nop30. While ARC interacts with caspase-2 and -8 and suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1 and DR3, Nop30 multimerizes and binds to |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 14 amino acid peptide from near the carboxy terminus of human Nop30. |
Other Names | [Nucleolar protein 3, Apoptosis repressor with CARD, ARC] |
Gene, Accession # | [Nop30], Gene ID: 8996, NCBI: AAH12798 |
Catalog # | MBS9411181 |
Price | $320 |
Order / More Info | Nop30 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |