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Antigenic Specificity | Vinculin |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion. |
Immunogen | Immunogen: A synthesized peptide derived from human Vinculin. Subcellular Localization: Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, focal adhesion. Cytoplasmic face of adhesion plaques. Recruitment to cell-cell junctions occurs in a myosin II- dependent manner. Interaction with CTNNB1 is necessary for its localization to the cell-cell junctions (By similarity). Colocalizes with LIMD1 in the focal adhesion |
Other Names | [Vinculin; Metavinculin; MV; VCL], [VCL; VCL; MV; MVCL; CMD1W; CMH15; HEL114; MV] |
Gene, Accession # | [VCL], Gene ID: 7414, NCBI: NP_003364.1, UniProt: P18206 |
Catalog # | MBS179590 |
Price | $160, $340, $340 |
Order / More Info | Vinculin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |