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Antigenic Specificity | FBXO7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: porcine, zebrafish, bovine, horse, sheep, rabbit, dog, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FBXO7 Antibody detects endogenous levels of FBXO7. Description: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PRKN to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.Subunit Structure: Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO7) formed of CUL1, SKP1, RBX1 and FBXO7. Interacts via its C-terminal proline-rich region with DLGAP5. Interacts with BIRC2. Interacts with CDK |
Immunogen | Immunogen: A synthesized peptide derived from human FBXO7. |
Other Names | [F box only protein 7; F box protein 7; F-box only protein 7; FBX; FBX07; FBX7; FBX7_HUMAN; Fbxo7; PARK15; PKPS] |
Gene, Accession # | [FBXO7], Gene ID: 25793, NCBI: NP_036311, UniProt: Q9Y3I1 |
Catalog # | MBS9611759 |
Price | $240, $280 |
Order / More Info | FBXO7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |