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Antigenic Specificity | CIAO1 |
Clone | [AT6C9] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1,k |
Format | Protein A purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CIAO1 is a essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. It is a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. CIAO1 seems to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation. As part of the mitotic spindle-associated MMXD complex, it may play a role in chromosome segregation. |
Immunogen | Immunogen: Recombinant human CIAO1 (1-339aa) purified from E. coli |
Other Names | [Probable cytosolic iron-sulfur protein assembly protein CIAO1; CIA1; WDR39], [CIAO1; CIAO1; CIA1; WDR39] |
Gene, Accession # | [CIAO1], Gene ID: 9391, NCBI: NP_004795, UniProt: O76071 |
Catalog # | MBS200262 |
Price | $240, $315 |
Order / More Info | CIAO1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Johnstone, RW., et al. (1998) J Biol Chem 273 (18): 10880-7; Srinivasan, V., et al. (2007) Structure 15: 1246-1257; Ito, S., et al. (2010) Mol Cell 39: 632-640 |