HIF2 alpha Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-HIF2 alpha antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | HIF2 alpha |
| Clone | [EP190B] |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 0.1 mg |
| Concentration | 1mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: ~100kDa. Specific for HIF2 Alpha. Background Info: Does not cross react with HIF1Alpha Scientific Background: Members of the hypoxia-inducible factor (HIF) family of transcription factors regulate the cellular response to hypoxia (1). HIF2-Alpha is involved in catecholamine homeostasis, vascular remodeling, physiological angiogenesis and adipogenesis. It is overexpressed in many cancerous tissues, but its exact role in tumour progression remains to be clarified (2). Studies suggest that in the case of non-small cell lung cancer, HIF2-Alpha actually is a promoter of tumor growth and progression in a solid tumor (1). Other data suggests that HIF2-Alpha is an important regulator of innate immunity, and therefore may be useful in t |
| Immunogen | Immunogen: GST-human EPAS-1 (HIF2alpha) amino acids 535-631 fusion protein. Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide. Certificate of Analysis: 1 ug/ml of SMC-185 was sufficient for detection of HIF2-alpha in 20 ug of CoCl2-induced Hela cell lystae by colorimetric immunoblot analysis using Goat anti-mouse IgG: HRP as the secondary antibody. Research Areas: Cancer| Oxidative stress| Cell Signaling| Epigenetics. Cellular Localization: Nucleus. |
| Other Names | [ECYT4; EPAS1; HIF2alpha; HIF1 Alpha like factor; HLF; Hypoxia inducible factor 2 alpha; MOP2; PASD2], [EPAS1; EPAS1; HLF; MOP2; ECYT4; HIF2A; PASD2; bHLHe73; BHLHE73; HIF2A; MOP2; PASD2; EPAS-1; bHLHe73; HLF; HIF-2-alpha; HIF2-alpha] |
| Gene, Accession # | Gene ID: 2034, NCBI: NP_001421, UniProt: Q99814 |
| Catalog # | MBS800144 |
| Price | $405 |
| Order / More Info | HIF2 alpha Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Kim W.Y., et al. (2009) J Clin Invest. 119(8): 2160-2170. 2. Favier J., Lapointe S., Maliba R. and Sirois M.G. (2007) BMC Cancer. 7:139. 3. Imtiyaz H.Z., et al. (2010) J Clin Invest. 120(8): 2699-2714. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies