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Antigenic Specificity | CKMT1A |
Clone | [AT17A2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b,k |
Format | Protein A purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CKMT1A, also known as Creatine kinase, mitochondrial 1A, is 417 amino acid protein. Mitochondrial creatine kinase (MtCK) exists as two isoenzymes, sarcomeric MtCK (CKMT2) and ubiquitous MtCK (CKMT1). It is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. |
Immunogen | Immunogen: Recombinant human CKMT1A (40-417aa) purified from E. coli |
Other Names | [Creatine kinase u-type mitochondrial; Creatine kinase u-type; mitochondrial; CKMT1; CKMT1B; uMTCK], [CKMT1A; CKMT1A; CKMT1; U-MtCK; mia-CK; CKMT; Mia-CK; U-MtCK] |
Gene, Accession # | [CKMT1A], Gene ID: 548596, NCBI: NP_001015001, UniProt: P12532 |
Catalog # | MBS200289 |
Price | $240, $315 |
Order / More Info | CKMT1A Antibody from MYBIOSOURCE INC. |
Product Specific References | Haas. R.C., et al. (1989) J Biol Chem 264 (5): 2890-2897 ; Stachowiak. O., et al. (1998) Mol Cell Biochem 184 (1-2): 141-151; Lipskaya. T.Y. (2001) Biochemistry Mosc 66 (10): 1098-1111 |