Edit |   |
---|---|
Antigenic Specificity | Acetyl-Histone H4 (Lys5) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkey |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of Histone H4 only when acetylated at Lysine 5. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around acetylation site of Lysine 5(S-G-R(p)-G-K) derived from Human Histone H4. |
Other Names | [H4, H4/n, H4F2, H4FN, FO108] |
Gene, Accession # | Gene ID: 554313, NCBI: NP_001029249.1, UniProt: P62805 |
Catalog # | MBS9408425 |
Price | $200, $255 |
Order / More Info | Acetyl-Histone H4 (Lys5) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |