APAF1 (aa12-28) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAPAF1 (aa12-28)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatunconjugated
Size0.1 mg
ConcentrationIgG concentration 0.5 mg/ml
ApplicationsImmunohistology Paraffin*, Western Blot (WB)
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DescriptionSpecificity: Apaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade characteristic of apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. This item recognises a 130kD band in Western blots. Apaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade characteristic of apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. MBS221594 recogni
ImmunogenImmunogen: Synthetic peptide corresponding to amino acids 12-28 of human Apaf1 Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human Apaf-1 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human
Other Names[apoptotic protease-activating factor 1 isoform b; Apoptotic protease-activating factor 1; apoptotic protease-activating factor 1; apoptotic peptidase activating factor 1], [APAF1; APAF1; CED4; APAF-1; KIAA0413; APAF-1]
Gene, Accession #[APAF1], Gene ID: 317, NCBI: NP_001151.1, UniProt: O14727
Catalog #MBS221594
Price$375
Order / More InfoAPAF1 (aa12-28) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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