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Antigenic Specificity | APAF1 (aa12-28) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 0.5 mg/ml |
Applications | Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Apaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade characteristic of apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. This item recognises a 130kD band in Western blots. Apaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade characteristic of apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. MBS221594 recogni |
Immunogen | Immunogen: Synthetic peptide corresponding to amino acids 12-28 of human Apaf1 Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human Apaf-1 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human |
Other Names | [apoptotic protease-activating factor 1 isoform b; Apoptotic protease-activating factor 1; apoptotic protease-activating factor 1; apoptotic peptidase activating factor 1], [APAF1; APAF1; CED4; APAF-1; KIAA0413; APAF-1] |
Gene, Accession # | [APAF1], Gene ID: 317, NCBI: NP_001151.1, UniProt: O14727 |
Catalog # | MBS221594 |
Price | $375 |
Order / More Info | APAF1 (aa12-28) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |