Edit |   |
---|---|
Antigenic Specificity | DDX58 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DDX58 Antibody detects endogenous levels of total DDX58. Retinoic acid inducible gene I (RIG-I) is a 925 amino acid, interferon-inducible cellular DExD/H box RNA helicase that activates type I interferon (IFN), an important effector of the innate immune system that is sensitive to these dsRNA viruses. dsRNA is normally present in very low quantities in cells, so when a virus is present, the elevated levels of dsRNA act as a sign telling RIG-I to activate the production of IFN. |
Immunogen | Immunogen: A synthesized peptide derived from human DDX58 |
Other Names | [RIG-I-like receptor 1; RLR-1; RLR1; Retinoic acid-inducible gene 1 protein; RIG-1; RIG1; RIG-I; RIGI] |
Gene, Accession # | [DDX58], Gene ID: 23586, NCBI: NP_055129.2, UniProt: O95786 |
Catalog # | MBS4751029 |
Price | $335 |
Order / More Info | DDX58 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |