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Antigenic Specificity | TIMP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: bovine, horse, sheep, rabbit, dog, chicken |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TIMP2 Antibody detects endogenous levels of total TIMP2. Description: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.Post Translational Modifications: The activity of TIMP2 is dependent on the presence of disulfide bonds.Subunit Structure: Interacts (via the C-terminal) with MMP2 (via the C-terminal PEX domain); the interaction inhibits the MMP2 activity.Similarity: Belongs to the protease inhibitor I35 (TIMP) family. |
Immunogen | Immunogen: A synthesized peptide derived from human TIMP2. Tissue Specificity: Down-regulated by TGFB1. |
Other Names | [CSC 21K; CSC-21K; CSC21K; Metalloproteinase inhibitor 2; Metalloproteinase inhibitor 2 precursor; TIMP 2; TIMP metallopeptidase inhibitor 2; TIMP-2; TIMP2; TIMP2_HUMAN; Tissue Inhibitor of Metalloproteinase 2; Tissue inhibitor of metalloproteinases 2] |
Gene, Accession # | [TIMP2], Gene ID: 7077, NCBI: NP_003246.1, UniProt: P16035 |
Catalog # | MBS9610370 |
Price | $225, $280, $340 |
Order / More Info | TIMP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |