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Antigenic Specificity | Ig Lambda Chain, Human |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 5 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Formalin/Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The anti-lambda antibody may be used for the detection of abnormal immunoglobulin production, e.g. monoclonal gammopathy with increased production of both free and bound lambda chains. In this context the differentiation from kappa light chains or heavy chains is of importance. The antibody stains B-cells in lymphoidal tissue and peripheral blood as well as plasma cells expriming lambda chains (especially useful in formaldehyde-fixed paraffin sections). Reed-Sternberg-Cells may be stained if exogenous Ig has been absorbed. The antibody may be helpful for the detection of the monoclonal nature of lymphoidal neoplasms. Immunoglobulins are composed of heavy and light chains and the light chains may be of the kappa or lambda type. In humans app |
Immunogen | Immunogen: Purified human myeloma-IgG polyaminostyrene conjugate |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS397247 |
Price | $255 |
Order / More Info | Ig Lambda Chain, Human Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. N. Leung, S. V. Rajkumar (2007) Renal Manifestations of Plasma Cell Disorders. American Journal of Kidney Diseases 50; 155-165. 2. Markowitz GS (2004) Dysproteinemia and the kidney. Adv Anat Pathol 11:49-63. |