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Antigenic Specificity | Bcl-w |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Bcl-w Polyclonal Antibody detects endogenous levels of Bcl-w protein. BCL2L2 encodes a member (BCL2 like 2)of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of BCL2L2 in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly (A) binding p |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human Bcl-w at AA range: 100-180 |
Other Names | [Rabbit Bcl-w; BCL2L2; BCLW; KIAA0271; Bcl-2-like protein 2; Bcl2-L-2; Apoptosis regulator Bcl-W] |
Gene, Accession # | [BCL-W], Gene ID: 599, NCBI: NP_001186768.1, UniProt: Q92843 |
Catalog # | MBS9701492 |
Price | $130, $220, $325 |
Order / More Info | Bcl-w Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |