Human ASK1 (pSer83) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Human ASK1 (pSer83) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mg |
| Concentration | IgG concentration 2.0mg/ml |
| Applications | ELISA (EIA), Western Blot (WB)* |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item detects Apoptosis Signal-regulating Kinase 1 (ASK1) phosphorylated at serine83. ASK1 is a serine/threonine kinase also known as MAP kinase kinase kinase (MAPKKK), and plays an important role in the apoptotic response to various stimuli including oxidative stress, cytokines (e.g. TNF) and endoplasmic reticulum stress. Akt in conjunction to Hsp90 phosphorylates ASK1 at Ser83 to inhibit ASK1 induced apoptosis. MBS221528 detects Apoptosis Signal-regulating Kinase 1 (ASK1) phosphorylated at serine83. ASK1 is a serine/threonine kinase also known as MAP kinase kinase kinase (MAPKKK), and plays an important role in the apoptotic response to various stimuli including oxidative stress, cytokines (e.g. TNF) and endoplasmic reticulum stress. |
| Immunogen | Immunogen: KLH conjugated peptide corresponding to amino acids 76-87 of human ASK-1 protein. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to ASK1 (pSER83) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by ion exchange chromatography. Target Species: Human |
| Other Names | [mitogen-activated protein kinase kinase kinase 5; Mitogen-activated protein kinase kinase kinase 5; mitogen-activated protein kinase kinase kinase 5; ASK-1; MAP/ERK kinase kinase 5; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5; apoptosis signal regulating kinase 1; apoptosis signal-regulating kinase 1; mitogen-activated protein kinase kinase kinase 5; Apoptosis signal-regulating kinase 1; ASK-1; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5], [MAP3K5; MAP3K5; ASK1; MEKK5; MAPKKK5; ASK1; MAPKKK5; MEKK5; ASK-1; MEK kinase 5; MEKK 5] |
| Gene, Accession # | [ASK1], Gene ID: 4217, NCBI: NP_005914.1, UniProt: Q99683 |
| Catalog # | MBS221528 |
| Price | $250 |
| Order / More Info | Human ASK1 (pSer83) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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