NOD1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-NOD1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | NOD1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Nod1/CARD4 is a cytosolic protein structually related to Apaf-1 and plant drug-resistance proteins that has been implicated in apoptosis and inflammatory responses to certain pathogenic bacteria (1-3). It contains an amino-terminal caspase recruitment domain (CARD) that is linked to a central nucleotide-binding domain (NBD; also known as a NOD domain) and is followed by carboxy-terminal leucine-rich repeats (LRR) (1). Like Apaf-1, Nod1 induces apoptosis by a CARD/NBD-dependent activation of caspase-9 (1). The primary function of Nod1 is thought to be as a sensor for certain pathogenic microbes and triggering inflammatory responses including the activation of NF-kappaB and JNK pathways (4-6). The LRR of Nod1 appears to be involved in recogni |
| Immunogen | Immunogen: Recombinant protein of human NOD1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [NOD1; CARD4; CLR7.1; NLRC1] |
| Gene, Accession # | [NOD1], Gene ID: 10392, NCBI: NP_006083.1, UniProt: Q9Y239 |
| Catalog # | MBS8500791 |
| Price | $310 |
| Order / More Info | NOD1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Inohara, N. et al. (1999) J. Biol. Chem. 274, 14560-14567. 2. Inohara, N. and Nunez, G. (2003) Nat. Rev. Immunol. 3, 371-382. 3. Fritz, J.H. et al. (2006) Nat.Immunol. 7, 1250-1257. 4. Girardin, S.E. et al. (2001) EMBO Rep. 2, 736-742. 5. Inohara, N. et al. (2001) J. Biol. Chem. 276, 2551-2554. 6. Inohara, N. et al. (2000) J. Biol. Chem. 275, 27823-27831. 7. Hysi, P. et al. (2005) Hum. Mol. Genet. 14, 935-941. 8. McGovern, D.P. et al. (2005) Hum. Mol. Genet. 14, 1245-1250. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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