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Antigenic Specificity | IL19 |
Clone | [257] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-19,a member of the IL-10 cytokine family,is expressed in epithelial cells,endothelial cells,and macrophages. It can bind the interleukin-20 receptor complex IL-20R1/IL-20R2 and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). IL-19 induces IL-6 and TNF-alpha production in monocytes. It also induces cell apoptosis and reactive oxygen species production in monocytes, which suggests a role of this cytokine in inflammatory responses. It is upregulated in monocytes following stimulation with lipopolysaccharide (LPS), and granulocyte-macrophage colony-stimulating factor (GM-CSF). IL-19 alters the balance of Th1 and Th2 cells in favor of Th2 cells. IL-19 contributes to a range of diseases and disorders,s |
Immunogen | Immunogen: Fusion protein of IL-19 |
Other Names | [IL 10C,IL 19,IL19,interleukin 19,MDA1,NG.1,ZMDA1] |
Gene, Accession # | [IL19], Gene ID: 29949, NCBI: NP_037503.2, UniProt: Q9UHD0 |
Catalog # | MBS2541949 |
Price | $220, $290, $435 |
Order / More Info | IL19 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |