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Antigenic Specificity | Human ROR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg, 0.2 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ROR2 is a signaling receptor for Wnt ligands that is known to play important roles in limb development, but having no essential roles known in adult tissues. Recent evidence has implicated ROR2 in mediating both canonical and non-canonical signaling pathways. ROR2 was initially found to be highly expressed in osteosarcoma and renal cell carcinomas, and has recently been found in an increasingly long list of cancers currently including melanoma, colon cancer, melanoma, squamous cell carcinoma of the head and neck, and breast cancer. In the majority of these cancer types, ROR2 expression is associated with more aggressive disease states, consistent with a role mediating Wnt signaling regardless of the canonical or non-canonical signal. Becaus |
Immunogen | Antibody Generation: Produced from sera of rabbits immunized with highly pure recombinant human soluble ROR2. Anti-human ROR2 specific antibody was purified by Protein-A chromatography. Antigen: Recombinant Human sROR2 |
Other Names | [Neurotrophic tyrosine kinase; receptor-related 2], [ROR2; ROR2; BDB; BDB1; NTRKR2; NTRKR2] |
Gene, Accession # | [ROR2], Gene ID: 4920, NCBI: NP_001305133.1, UniProt: Q01974 |
Catalog # | MBS692259 |
Price | $280, $390 |
Order / More Info | Human ROR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |