Edit |   |
---|---|
Antigenic Specificity | Human TGF-beta2 |
Clone | [6M28] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TGF-beta 2 belongs to the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1;7)(q41;p21) between this gene and HDAC9 is associated with Peters\' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice |
Immunogen | Antigen: Recombinant human TGF-beta 2 Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with recombinant human TGF-beta2). The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized. |
Other Names | [Transforming growth factor beta-2; BSC-1 cell growth inhibitor; Cetermin; Glioblastoma-derived T-cell suppressor factor; G-TSF; Polyergin], [TGFB2; TGFB2; LDS4; TGF-beta2; TGF-beta-2; G-TSF; LAP] |
Gene, Accession # | [TGF-beta2], Gene ID: 7042, NCBI: NP_001129071.1, UniProt: P61812 |
Catalog # | MBS692196 |
Price | $490 |
Order / More Info | Human TGF-beta2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |