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Antigenic Specificity | HBG2 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HBG2 |
Other Names | [hemoglobin subunit gamma-2; Hemoglobin subunit gamma-2; hemoglobin subunit gamma-2; hemoglobin subunit gamma 2; Gamma-2-globin; Hb F Ggamma; Hemoglobin gamma-2 chain; Hemoglobin gamma-G chain] |
Gene, Accession # | [HBG2], Gene ID: 3048, NCBI: NP_000175.1, UniProt: P69892 |
Catalog # | MBS3220292 |
Price | $335 |
Order / More Info | HBG2 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |