Human Gamma-aminobutyric acid type B receptor subunit 2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Gamma-aminobutyric acid type B receptor subunit 2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release b |
| Immunogen | Immunogen: Recombinant human Gamma-aminobutyric acid type B receptor subunit 2 protein (60-310aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22322 / sc-31457 / sc-31459 / sc-28792 |
| Other Names | [GABA-B receptor 2; GABA-B-R2; GABA-BR2; GABABR2; Gb2; G-protein coupled receptor 51; GABBR2; GPR51; GPRC3B], [GABBR2; GABBR2; HG20; GPR51; GPRC3B; GABABR2; HRIHFB2099; GPR51; GPRC3B; GABA-B receptor 2; GABA-B-R2; GABA-BR2; GABABR2; Gb2] |
| Gene, Accession # | [GABBR2], Gene ID: 9568, NCBI: NP_005449.5, UniProt: O75899 |
| Catalog # | MBS1497467 |
| Price | $120, $160 |
| Order / More Info | Human Gamma-aminobutyric acid type B receptor subunit 2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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