Human GPR44 / CRTH2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman GPR44 / CRTH2
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesgorilla, human
Isotypen/a
Formatimmunoaffinity purified
Size0.05 mg
Concentration1 mg/ml
ApplicationsImmunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
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DescriptionSpecificity: Residues 329-348 [DDSELGGAGSSRRRRTSSTA] of the CRTH2 (GPR44) protein. This sequence is near the C terminus. GPR44, also called CRTH2, is a Prostanoid Receptor that binds prostaglandin D2. PGD2 signals through CRTH2 to induce Th2, eosinophil, and basophil chemotaxis in a G-alpha(i) dependent manner. CRTH2 may play a role in mast cell-mediated immune responses such as those involved in allergic reactions. This receptor is upregulated in activated T helper-2 (Th2) cells, peripheral blood basophils, and eosinophils, but not in Th1 lineage cells. It may be a useful marker for Th2 and Tc2 cells.
ImmunogenImmunogen Description: Synthetic peptide from human GPR44 / CRTH2. Percent identity by BLAST analysis: Human, Gorilla (100%); Pig (85%); Elephant (80%).
Other Names[GPR44 / CRTH2 (aa329-348) IHC-plus; PTGDR2; CD294; CRTH2; CD294 antigen; DP2; DL1R; G protein-coupled receptor 44; G-protein coupled receptor 44; HCRTH2; DP2 prostaglandin receptor; GPR44; Prostaglandin D2 receptor 2; Human GPR44; CRTH2], [CRTH2; PTGDR2]
Gene, Accession #[GPR44], Gene ID: 11251, NCBI: NP_004769.2, UniProt: Q9Y5Y4
Catalog #MBS244950
Price$530
Order / More InfoHuman GPR44 / CRTH2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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