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Antigenic Specificity | Human GPR44 / CRTH2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | gorilla, human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Residues 329-348 [DDSELGGAGSSRRRRTSSTA] of the CRTH2 (GPR44) protein. This sequence is near the C terminus. GPR44, also called CRTH2, is a Prostanoid Receptor that binds prostaglandin D2. PGD2 signals through CRTH2 to induce Th2, eosinophil, and basophil chemotaxis in a G-alpha(i) dependent manner. CRTH2 may play a role in mast cell-mediated immune responses such as those involved in allergic reactions. This receptor is upregulated in activated T helper-2 (Th2) cells, peripheral blood basophils, and eosinophils, but not in Th1 lineage cells. It may be a useful marker for Th2 and Tc2 cells. |
Immunogen | Immunogen Description: Synthetic peptide from human GPR44 / CRTH2. Percent identity by BLAST analysis: Human, Gorilla (100%); Pig (85%); Elephant (80%). |
Other Names | [GPR44 / CRTH2 (aa329-348) IHC-plus; PTGDR2; CD294; CRTH2; CD294 antigen; DP2; DL1R; G protein-coupled receptor 44; G-protein coupled receptor 44; HCRTH2; DP2 prostaglandin receptor; GPR44; Prostaglandin D2 receptor 2; Human GPR44; CRTH2], [CRTH2; PTGDR2] |
Gene, Accession # | [GPR44], Gene ID: 11251, NCBI: NP_004769.2, UniProt: Q9Y5Y4 |
Catalog # | MBS244950 |
Price | $530 |
Order / More Info | Human GPR44 / CRTH2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |