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Antigenic Specificity | IL26 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IL26 antibody detects endogenous levels of total IL26. Function: May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.Subunit Structure: Homodimer.Similarity: Belongs to the IL-10 family. |
Immunogen | Immunogen: A synthesized peptide derived from human IL26 Subcellular Location: Secreted. Tissue Specificity: Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells. Expressed in colonic T-cells including Th17 inflammatory T-cells; the expression is significantly increased in serum of patients with Crohn's disease (at protein level). Predicted Cross Reactivity: Pig, Rabbit Similarity: Pig (82%), Rabbit (80%) |
Other Names | [AK155; IL 26; IL-26; IL26; IL26_HUMAN; Interleukin 26; Interleukin-26; Protein AK155] |
Gene, Accession # | [IL26], Gene ID: 55801, NCBI: NP_060872.1, UniProt: Q9NPH9 |
Catalog # | MBS9609300 |
Price | $240, $280 |
Order / More Info | IL26 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |