Cytochrome C (Mitochondrial Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Cytochrome C (Mitochondrial Marker) |
| Clone | polyclonal |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat, horse, dog, pigeon, frog, Drosophila |
| Isotype | n/a |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: It recognizes an epitope within amino acids 93-104 of pigeon Cytochrome C, a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown t |
| Immunogen | Immunogen: Synthetic peptides corresponding to amino acid 1-80, 81-104 and 66-104 of pigeon cytochrome c |
| Other Names | [CYC; CYCS; HCS; THC4] |
| Gene, Accession # | [CYCS], Gene ID: 54205, NCBI: NP_061820.1, UniProt: P99999 |
| Catalog # | MBS4381178 |
| Price | $190, $340, $340 |
| Order / More Info | Cytochrome C (Mitochondrial Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Goshorn SG., et al. J Biol Chem 266:2134-2142 (1991). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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