HSP90 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | HSP90 |
| Clone | [H9010] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat, rabbit, chicken, dog, fish, White Sucker fish, shark, Gummy shark, School shark, hamster |
| Isotype | IgG2a |
| Format | Protein G purified |
| Size | 0.05 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA (EIA), Antibody Microarray (AM) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects 90kDa. Detects HSP90 beta in all reactive species except in Chicken, where it detects both alpha and beta isoforms. HSP90 is an abundantly and ubiquitously expressed heat shock protein. It is understood to exist in two principal forms alpha and beta, which share 85% sequence amino acid homology. The two isoforms of HSP90, are expressed in the cytosolic compartment (1). Despite the similarities, HSP90alpha exists predominantly as a homodimer while HSP90beta exists mainly as a monomer (2). From a functional perspective, HSP90 participates in the folding, assembly, maturation, and stabilization of specific proteins as an integral component of a chaperone complex (3-6). Furthermore, HSP90 is highly conserved between species; having 60% |
| Immunogen | Immunogen: Recombinant human HSP90beta Immunogen Species: Human |
| Other Names | [Mouse Human HSP90 IgG2a; HSP90, Clone H9010; HSP84; HSP90; HSP90 beta; HSP90B; HSPC2; HSPCB] |
| Gene, Accession # | [HSP90], Gene ID: 3326, NCBI: NP_001258898.1, UniProt: P08238 |
| Catalog # | MBS8001862 |
| Price | $245 |
| Order / More Info | HSP90 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Nemoto T., et al. (1997) J.Biol Chem. 272: 26179-26187. 2. Minami Y., et al. (1991), J.Biol Chem. 266: 10099-10103. 3. Arlander S.J.H., et al. (2003) J Biol Chem 278: 52572-52577. 4. Pearl H., et al. (2001) Adv Protein Chem 59:157-186. 5. Neckers L., et al. (2002) Trends Mol Med 8:S55-S61. 6. Pratt W., Toft D. (2003) Exp Biol Med 228:111-133. 7. Pratt W., Toft D. (1997) Endocr Rev 18:306-360. 8. Pratt W.B. (1998) Proc Soc Exptl Biol Med 217: 420-434. 9. Whitesell L., et al. (1994) Proc Natl Acad Sci USA 91: 8324-8328. 10. Barent R. L. (1998) Mol. Endocrinol. 12: 342-354 11. Lo. M.A. (1998) EMBO J. 17: 6879-6887. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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