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Antigenic Specificity | Caspase 9 (Phospho-Thr125) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antiserum was produced against synthesized phosphopeptide derived from human Caspase 9 around the phosphorylation site of threonine 125 (P-E-TP-P-R). Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9. |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of threonine 125 (P-E-T(p)-P-R) derived from Human Caspase 9. |
Other Names | [APAF-3; MCH6; RNCASP9; CASP-9; ICE-LAP6] |
Gene, Accession # | Gene ID: 842, NCBI: NP_001220.2, UniProt: P55211 |
Catalog # | MBS9401058 |
Price | $200, $255 |
Order / More Info | Caspase 9 (Phospho-Thr125) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |