CYTC Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCYTC
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Several alternatively spliced transcript variants encoding different isoforms have been identified for th
ImmunogenImmunogen: A synthetic peptide of human PSEN1. Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[AD3; FAD; PS1; PS-1; S182], [PSEN1; PSEN1; AD3; FAD; PS1; PS-1; S182; ACNINV3; AD3; PS1; PSNL1; PS-1; PS1-CTF12]
Gene, Accession #[CYTC], Gene ID: 5663, NCBI: NP_000012.1, UniProt: P49768
Catalog #MBS859811
Price$290
Order / More InfoCYTC Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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