KHDRBS1 (Center) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKHDRBS1 (Center)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatunconjugated
Size0.05 mL, 0.2 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Paraffin, Western Blot (WB)
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DescriptionRecruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain- containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export. Positively regulates the association of constitutive transport element (CTE)-containing mRNA with large polyribosomes and translation initiation. According to some authors, is not involved in the nucleocytoplasmi
Immunogenn/a
Other Names[Purified Rabbit (Pab); KH domain-containing; RNA-binding; signal transduction-associated protein 1; GAP-associated tyrosine phosphoprotein p62; Src-associated in mitosis 68 kDa protein; Sam68; p21 Ras GTPase-activating protein-associated p62; p68; KHDRBS1 (HGNC:18116)]
Gene, Accession #[KHDRBS1], Gene ID: 10657, NCBI: NP_001258807.1, UniProt: Q07666
Catalog #MBS9216941
Price$165, $370
Order / More InfoKHDRBS1 (Center) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesWong G.,et al.Cell 69:551-558(1992). Barlat I.,et al.J. Biol. Chem. 272:3129-3132(1997). Ota T.,et al.Nat. Genet. 36:40-45(2004). Gregory S.G.,et al.Nature 441:315-321(2006). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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