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Antigenic Specificity | DUSP6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by DUSP6 (dual specificity phosphatase 6) is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP6 product inactivates ER |
Immunogen | Immunogen: Synthetic Peptide |
Other Names | [Rabbit DUSP6; DUSP6; MKP3; PYST1; Dual specificity protein phosphatase 6; Dual specificity protein phosphatase PYST1; Mitogen-activated protein kinase phosphatase 3; MAP kinase phosphatase 3; MKP-3] |
Gene, Accession # | [DUSP6], Gene ID: 1848, NCBI: NP_001937.2, UniProt: Q16828 |
Catalog # | MBS9707967 |
Price | $130, $220, $325 |
Order / More Info | DUSP6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |