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Antigenic Specificity | Human Thioredoxin-2 |
Clone | [PAT1B1AT] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b k |
Format | Protein G purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Thioredoxin-2 is a low molecular weight redox protein. TRX2 contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The TXN2 is involved in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. Upon stimulation of Fas, TXN2 mediates denitrosylation of mitochondria-associated caspase-3, a process required for caspase-3 activation, and promoted apoptosis.TRX2 is important at low oxidative stress conditions.MTRX is involved in the regulation of the mitochondrial membrane potential and cell death. Mitochondrial thioredoxin plays an important roles in protection against oxidant-induced apoptosis. Thioredoxin1 and thioredoxin2 have opposed regulatory f |
Immunogen | Immunogen: Anti-human TXN2 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TXN2 protein 60-166 amino acids purified from E Coli. |
Other Names | [TXN2; Thioredoxin mitochondrial; Thioredoxin-2; TXN2; MTRX; TRX2; MT-TRX; TRX-2; TXN-2; Thioredoxin-2, Mouse Human], [TRX2; TRX2; Arabidopsis thioredoxin h2; ATH2; ATTRX2; ATTRXH2; MYH19.110; MYH19_110; THIOREDOXIN; thioredoxin 2; THIOREDOXIN H2; TRXH2; AtTrxh2; AtTRX2] |
Gene, Accession # | [TXN2], Gene ID: 833992, NCBI: NP_198811.1, UniProt: Q38879 |
Catalog # | MBS146709 |
Price | $140, $205, $505 |
Order / More Info | Human Thioredoxin-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |