Grap Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGrap
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: Grap antibody detects endogenous levels of total Grap. Function: Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.Subunit Structure: Associates through its SH2 domain with ligand-activated receptors for stem cell factor (KIT) and erythropoietin (EPOR). Also forms a stable complex with the Bcr-Abl oncoprotein. GRAP is associated with the Ras guanine nucleotide exchange factor SOS1, primarily through its N-terminal SH3 domain. Interacts with phosphorylated LAT upon TCR activation. Interacts with SHB.Similarity: Belongs to the GRB2/sem-5/DRK family.
ImmunogenImmunogen: A synthesized peptide derived from human Grap Predicted Cross Reactivity: Pig, Bovine Similarity: Pig (100%), Bovine (100%)
Other Names[Grap; GRAP_HUMAN; GRB2 related adaptor protein; GRB2-related adapter protein; Growth factor receptor bound protein 2 related adaptor protein; MGC64880; OTTHUMP00000065766]
Gene, Accession #[Grap], Gene ID: 10750, NCBI: NP_001317077.1, UniProt: Q13588
Catalog #MBS9602122
Price$240, $280
Order / More InfoGrap Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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