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Antigenic Specificity | Grap |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Grap antibody detects endogenous levels of total Grap. Function: Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.Subunit Structure: Associates through its SH2 domain with ligand-activated receptors for stem cell factor (KIT) and erythropoietin (EPOR). Also forms a stable complex with the Bcr-Abl oncoprotein. GRAP is associated with the Ras guanine nucleotide exchange factor SOS1, primarily through its N-terminal SH3 domain. Interacts with phosphorylated LAT upon TCR activation. Interacts with SHB.Similarity: Belongs to the GRB2/sem-5/DRK family. |
Immunogen | Immunogen: A synthesized peptide derived from human Grap Predicted Cross Reactivity: Pig, Bovine Similarity: Pig (100%), Bovine (100%) |
Other Names | [Grap; GRAP_HUMAN; GRB2 related adaptor protein; GRB2-related adapter protein; Growth factor receptor bound protein 2 related adaptor protein; MGC64880; OTTHUMP00000065766] |
Gene, Accession # | [Grap], Gene ID: 10750, NCBI: NP_001317077.1, UniProt: Q13588 |
Catalog # | MBS9602122 |
Price | $240, $280 |
Order / More Info | Grap Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |