Human CD40 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD40
Clone[3A8]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a
Formatunconjugated
Size0.025 mg, 0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionCD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.
Immunogenn/a
Other Names[Human CD40; Tumor necrosis factor receptor superfamily member 5; Cd40; B-cell surface antigen CD40; Bp50; CD40L receptor; CD40; Tnfrsf5]
Gene, Accession #[CD40], Gene ID: 958, NCBI: NP_001241.1, UniProt: P25942
Catalog #MBS2553807
Price$85, $145
Order / More InfoHuman CD40 Antibody from MYBIOSOURCE INC.
Product Specific References1. Banchereau J, et al. 1994. Annu. Rev. Immunol. 12:881. 2. Foy T, et al. 1996. Annu. Rev. Immunol. 14:591.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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