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Antigenic Specificity | ITGA2B |
Clone | [80] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The integrins are a superfamily of cell adhesion receptors that bind to extracellular matrix ligands, cell-surface ligands, and soluble ligands. They are transmembrane alphabeta heterodimers and at least 24 distinct integrin heterodimers are formed by the combination of 18 alpha and eight beta known subunits. In addition to mediating cell adhesion, integrins also play important roles in modulating signal transduction pathways that control cellular responses including migration, proliferation, differentiation, and apoptosis. Integrin alpha-IIb (ITGA2B, CD41) is expressed on platelets, megakaryocytes and some hematopoietic progenitor cells. This protein undergoes post-translational cleavage to yield disulfide linked light and heavy chains whi |
Immunogen | Immunogen: Synthetic Peptide |
Other Names | [antigen CD41; BDPLT16; BDPLT2; CD41; CD41B; form 2; GP2B; GPalpha IIb; GPIIb; GT; GTA; HPA3; Integrin alpha 2b; Integrin alpha IIb; Integrin alpha-IIb light chain; Integrin; alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex; antigen CD41); ITA2B; Itga2b; ITGAB; platelet fibrinogen receptor; alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex; Platelet membrane glycoprotein IIb; platelet specific antigen BAK; PPP1R93; Integrin alpha 2b] |
Gene, Accession # | [ITGA2B], Gene ID: 3674, NCBI: NP_000410.2, UniProt: P08514 |
Catalog # | MBS2541858 |
Price | $220, $290, $435 |
Order / More Info | ITGA2B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |