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Antigenic Specificity | CD27 (C-term), 196-225 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.49 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CD27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-225 amino acids from the C-terminal region of human CD27. The protein encoded by this gene is a member of theTNF-receptor superfamily. This receptor is required for generationand long-term maintenance of T cell immunity. It binds to ligandCD70, and plays a key role in regulating B-cell activation andimmunoglobulin synthesis. This receptor transduces signals thatlead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteinsTRAF2 and TRAF5 have been shown to mediate the signaling process ofthis receptor. CD27-binding protein (SIVA), a proapoptotic protein,can bind to this receptor and is thought to pl |
Immunogen | n/a |
Other Names | [CD27 antigen; CD27L receptor; T-cell activation antigen CD27; T14; Tumor necrosis factor receptor superfamily member 7; CD27; CD27; TNFRSF7] |
Gene, Accession # | [CD27], Gene ID: 939, NCBI: NP_001233.1, UniProt: P26842 |
Catalog # | MBS9205328 |
Price | $165, $370 |
Order / More Info | CD27 (C-term), 196-225 Antibody from MYBIOSOURCE INC. |
Product Specific References | Jiang, J., et al. J. Clin. Immunol. 30(4):566-573(2010) Arimoto-Miyamoto, K., et al. Immunology 130(1):137-149(2010) Mizuochi, T., et al. J. Interferon Cytokine Res. 30(4):243-252(2010) Davila, S., et al. Genes Immun. 11(3):232-238(2010) Neron, S., et al. Arch. Immunol. Ther. Exp. (Warsz.) 57(6):447-458(2009) |