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Antigenic Specificity | TPM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Tropomyosin-1 (TPM1) belongs to the high molecular weight members of tropomyosin family (1,2). The protein exists in an alpha-helical coiled-coil conformation and binds multiple acting monomers in a tight manner to stabilize and regulate the actin filament (3). Tropomyosins fullfill functions in muscle and non-muscle cells. In muscle cells, tropomyosins associate with the troponin complex and play a central role in the calcium-dependent regulation of striated muscle contraction in vertebrates. In non-muscle cells, tropomyosins are implicated in the formation and stabilization of cytoskeletal actin filaments to ensure normal cellular processes (1,2). Mutations of tropomysin-1 have been reported as a cause of dilated cardiac myopathies (4). T |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [CMH3; TMSA; CMD1Y; C15orf13; HTM-alpha], [TPM1; TPM1; CMH3; TMSA; CMD1Y; LVNC9; C15orf13; HTM-alpha; C15orf13; TMSA] |
Gene, Accession # | [TPM1], Gene ID: 7168, NCBI: P09493.2, UniProt: P09493 |
Catalog # | MBS127505 |
Price | $200, $275, $430 |
Order / More Info | TPM1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |