HSP70/HSC70 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | HSP70/HSC70 |
| Clone | [BB70] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat, bovine, sheep, dog, beluga, fish, guinea pig, porcine, hamster, rabbit, chicken, African Clawed frog, Fruit Fly, yeast |
| Isotype | IgG2a |
| Format | Protein G purified |
| Size | 0.05 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~72 (HSP) and ~73kDa (HSC). HSP70 genes encode abundant heat-inducible 70-kDa HSPs (HSP70s). In most eukaryotes HSP70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplasmic reticulum and the cytosol, as well as in bacteria. The genes show a high degree of conservation, having at least 50% identity (2). The N-terminal two thirds of HSP70s are more conserved than the C-terminal third. HSP70 binds ATP with high affinity and possesses a weak ATPase activity which can be stimulated by binding to unfolded proteins and synthetic peptides (3). When HSC70 (constitutively expressed) present in mammalian cells was truncated, ATP binding |
| Immunogen | Immunogen: Chicken HSP70/HSP90 complex Immunogen Species: Chicken |
| Other Names | [Mouse Chicken HSP70/HSC70 IgG2a; HSP70/HSC70, Clone BB70; HSC54; HSC70; HSC71; HSP70 1; HSP701/HSP70 2; HSP70.1; HSP71; HSP72; HSP73; HSPA1; HSPA10; HSPA1A; HSPA1B; LAP1; NIP71] |
| Gene, Accession # | [HSP70/HSC70], Gene ID: 423504, NCBI: NP_001006686.1, UniProt: P08106 |
| Catalog # | MBS8001860 |
| Price | $245 |
| Order / More Info | HSP70/HSC70 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Zho J. (1998) Cell 94 : 471-480. 2. Boorstein W. R., Ziegelhoffer T. & Craig E. A. (1993) J. Mol. Evol.38 (1): 1-17. 3. Rothman J. (1989) Cell 59: 591-601. 4. DeLuca-Flaherty et al. (1990) Cell 62: 875-887. 5. Bork P., Sander C. & Valencia A. (1992) Proc. Nat Acad. Sci. USA 89: 7290-7294. 6. Fink A.L. (1999) Physiol. Rev. 79: 425-449. 7. Smith D.F., et al, (1993) Mol. Cell. Biol. 13(2): 869-876. 8. Prapapanich V., et al. (1996) Mol. Cell. Biol. 16(11):6200-6207. 9. Fernandez-Funez et al., (2000) Nature 408(6808): 101-106. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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