Hrs (HGS) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHrs (HGS)
Clone[19-5]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat, monkey
IsotypeIgG2b
Formatunconjugated
Size0.05 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
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DescriptionThe antibody recognizes an epitope is located between the VHS and coiled-coil domain of the HRS protein. Hepatocyte growth factor-regulated tyrosine kinase substrate (HRS, also known as HGS) is a mammalian protein predominantly localized on early endosomes. Hrs interacts with many proteins involved in membrane trafficking, such as eps15, SfdMdlSNAP-25. Hrs is implicated in early endosome fusion and may play a role in cargo sorting/trafficking to early and late endosome by recruiting clathrin. Hrs is also involved in intracellular signal transduction mediated by cytokines and growth factors.
ImmunogenImmunogen: Full length hrs-2 fusion protein
Other Namesn/a
Gene, Accession #[HRS]
Catalog #MBS588094
Price$415
Order / More InfoHrs (HGS) Antibody from MYBIOSOURCE INC.
Product Specific References1. Ronning SB-CIN85 regulates ubiquitination and degradative endosomal sorting of the EGF receptor. 2. Pullan L-The endosome-associated protein Hrs is hexameric and controls cargo sorting as a master molecule. 3. Tsujimoto S-The cellular and developmental expression of hrs-2 in rat.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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