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Antigenic Specificity | LGR6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: LGR6 antibody detects endogenous levels of total LGR6. Function: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.Similarity: Belongs to the G-protein coupled receptor 1 family. |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane Predicted Cross Reactivity: Rabbit Similarity: Rabbit (83%) |
Other Names | [FLJ14471; Gonadotropin receptor; GPCR; Leucine rich repeat containing G protein coupled receptor 6; Leucine-rich repeat-containing G-protein coupled receptor 6; Lgr6; LGR6_HUMAN; VTS20631] |
Gene, Accession # | [LGR6], Gene ID: 59352, NCBI: NP_001017403.1, UniProt: Q9HBX8 |
Catalog # | MBS9606435 |
Price | $240, $280 |
Order / More Info | LGR6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |