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Antigenic Specificity | SMAD4 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, goat, guinea pig, horse, human, mouse, rabbit, rat, sheep |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against SMAD4. It was validated on Western Blot using a cell lysate as a positive control.Target Description: SMAD4 is one of the Smad family members, which are essential intracellular signalling components of the transforming growth factor-beta (TGF-beta) superfamily. Smad2 and Smad3 are structurally highly similar and mediate TGF-beta signals. Smad4 is distantly related to Smads 2 and 3, and forms a heteromeric complex with Smad2 after TGF-beta or activin stimulation. TGF-beta induces heteromeric complexes of Smads 2, 3 and 4, and their concomitant translocation to the nucleus, which is required for efficient TGF-beta signal transduction |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SMAD4 |
Other Names | [mothers against decapentaplegic homolog 4; Mothers against decapentaplegic homolog 4; mothers against decapentaplegic homolog 4; SMAD family member 4; Deletion target in pancreatic carcinoma 4; SMAD family member 4] |
Gene, Accession # | [SMAD4], Gene ID: 4089, NCBI: NP_005350, UniProt: Q13485 |
Catalog # | MBS3200702 |
Price | $290 |
Order / More Info | SMAD4 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |